The Silfen Forum Participants

J. Larry Jameson, MD, PhD
President, University of Pennsylvania
Trustees University Professor

J. Larry Jameson, MD, PhD, has served as President of the University of Pennsylvania since March 2025, following his service as Interim President beginning in December 2023. He previously led Penn Medicine for more than a decade as Executive Vice President of the University of Pennsylvania for the Health System and Dean of the Raymond and Ruth Perelman School of Medicine. 

Under Dr. Jameson’s leadership, the University is pursuing Penn Forward to help shape Penn’s future priorities and direction. He champions the University’s core commitments to access, innovation, interdisciplinary collaboration, and societal impact. Milestones include the Quaker Commitment, which expands undergraduate financial aid; new cutting edge facilities for data science, computing, energy science, design, and the performing arts; the nation’s first Ivy League undergraduate degree program in artificial intelligence; major initiatives to advance climate science and the arts; and expanding Penn’s presence in Washington, D.C., to support civic engagement and policy leadership. 

During his tenure leading Penn Medicine, Dr. Jameson oversaw the opening of the largest capital project in the University’s history and the creation of the Serving a Changing World strategic plan. His leadership helped accelerate breakthroughs in CAR T cell therapy, gene-based treatments, and mRNA technology, while fostering a culture of excellence in patient care, research, and education. 

Before joining Penn in 2011, Dr. Jameson was Dean of Northwestern University’s Feinberg School of Medicine and Vice President for Medical Affairs. Earlier, he rose through the ranks at Harvard Medical School to become an associate professor of medicine and chief of the Thyroid Unit at Massachusetts General Hospital. 

A leading physician-scientist, Dr. Jameson has made seminal contributions to understanding the genetic basis of hormonal disorders. He has authored more than 350 scientific publications, co-edited Harrison’s Principles of Internal Medicine, and held leadership roles in major medical and scientific organizations. His honors include election to the National Academy of Medicine and the American Academy of Arts and Sciences, as well as awards from the Endocrine Society, the American Thyroid Association, and the American College of Surgeons.